The lab reconstructs synaptic connectivity using two-photon imaging and optogenetic perturbation. Current work characterizes how circuits reorganize as animals acquire new behaviors.

The group develops deep learning models that predict regulatory activity directly from DNA sequence. Ongoing studies relate noncoding variation to disease risk across diverse populations.

Research pairs psychophysics with neural recording to trace how the visual system constructs stable percepts. A central aim is to formalize how attention shapes perceptual inference.

The lab designs synthetic receptors that reprogram immune cells to recognize tumors. Recent efforts improve the precision and durability of engineered cell therapies.